Apolipoprotein E limits oxidative stress-induced cell dysfunctions in human adipocytes
نویسندگان
چکیده
منابع مشابه
Role of FoxO1 in FFA-induced oxidative stress in adipocytes.
Reactive oxygen species (ROS) production has recently been established as an essential contributor in the pathogenesis of obesity-associated insulin resistance. The FoxO1 pathway plays a role not only in nutrient sensing but also in regulating ROS production. We exposed adipocytes to free fatty acids (FFA) and demonstrated that FoxO1 protein levels decrease in a dose-dependent manner. The FoxO1...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2009
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2009.05.016